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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 384873Generated: October 25, 2026

5-Bromo-2-iodotoluene → 3-(4-Bromo-2-methyl-phenyl)-5-fluoro-pyridine

https://huagongshe.com/reaction/384873

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-iodotolueneHCID 2724601—
Reactant(5-Fluoropyridin-3-yl)boronic acidHCID 44717403—
Product3-(4-Bromo-2-methyl-phenyl)-5-fluoro-pyridineHCID 68409948—

Reaction Steps

The title compound was prepared from 5-bromo-2-iodotoluene and 5-fluoropyridine-3-boronic acid in analogy to Example 1b): MS (ISP): 265.8 and 267.9 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367838B2
Source datasetuspto-grants-2013_02
ORD IDord-6fd71ae0629f40fcba69883a937a761d
Source noteuspto-grants-2013_02