3-Furanol, tetrahydro- → 5-Bromo-2-[(oxolan-3-yl)oxy]pyridine

HRID 384878Notes

Reaction equation

HRID 384878 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:8])=[N:6][CH:7]=1.O[CH:10]1[CH2:14][CH2:13][O:12][CH2:11]1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:8][CH:10]2[CH2:14][CH2:13][O:12][CH2:11]2)=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 99603-Furanol, tetrahydro-HCID 178515818HCID 178515818, compound

Product 1

HCID 219142665-Bromo-2-[(oxolan-3-yl)oxy]pyridine

Procedure

The title compound was prepared from 5-bromo-2-hydroxypyridine and rac-3-hydroxy-tetrahydrofuran in analogy to Example 9c): colorless solid.

Sources & evidence

ORD record
ord-83ddf160321c4c898ae825cc9492b3b7
Source dataset
uspto-grants-2013_02
Patent number
US08367838B2

Reaction notes

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