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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 384879Generated: October 25, 2026

Tetrahydro-4H-pyran-4-ol → 4-(4-Bromo-2,6-difluoro-phenoxy)-tetrahydro-pyran

https://huagongshe.com/reaction/384879

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydro-4H-pyran-4-olHCID 74956—
Reactant4-Bromo-2,6-difluorophenolHCID 2736292—
Product4-(4-Bromo-2,6-difluoro-phenoxy)-tetrahydro-pyranHCID 68409276—

Reaction Steps

The title compound was prepared from 4-bromo-2,6-difluorophenol and tetrahydro-4H-pyran-4-ol in analogy to Example 9c): MS (EI): 292 and 294 M+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367838B2
Source datasetuspto-grants-2013_02
ORD IDord-caf70b5253454db490934fa4fd423ba1
Source noteuspto-grants-2013_02