4-Bromo-3-fluorophenol → HCID 68409002, compound

HRID 384887Notes

Reaction equation

HRID 384887 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[F:9].O[CH2:11][CH:12]1[CH2:15][CH2:14][O:13]1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:11][CH:12]2[CH2:15][CH2:14][O:13]2)=[CH:4][C:3]=1[F:9]

Participants

3

Reactant 2

HCID 27791534-Bromo-3-fluorophenolHCID 12284142(Oxetan-2-yl)methanol

Product 1

HCID 68409002HCID 68409002, compound

Procedure

The title compound was prepared from 4-bromo-3-fluorophenol and rac-2-hydroxymethyl-oxetane in analogy to Example 9c): MS (EI): 260 and 262 M+.

Sources & evidence

ORD record
ord-226713f88ae14294b2d912f3eff99f4f
Source dataset
uspto-grants-2013_02
Patent number
US08367838B2

Reaction notes

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