HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1-Bromo-2-fluoro-4-(2,2,3,3,3-pentafluoro-propoxy)-benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2,2,3,3,3-Pentafluoropropyl trifluoromethanesulfonate | HCID 2776019 | — |
| Reactant | 4-Bromo-3-fluorophenol | HCID 2779153 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1-Bromo-2-fluoro-4-(2,2,3,3,3-pentafluoro-propoxy)-benzene | HCID 87443298 | — |
Reaction Steps
The title compound was prepared from 4-bromo-3-fluorophenol and 2,2,3,3,3,-pentafluoropropyl triflate with potassium carbonate in acetone at ambient temperature for 18 hours. Kugelrohr distillation provided a colorless oil, b.p. 105-110° C./12 mbar.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367838B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-7ef815b8595f4da1b115d094560517b9 |
| Source note | uspto-grants-2013_02 |