HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-iodotoluene → Rac-[2-(4-bromo-2-methyl-phenyl)-1-(3,4-dichloro-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-iodotoluene | HCID 2724601 | — |
| Reactant | Rac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester | HCID 87442373 | — |
| Product | Rac-[2-(4-bromo-2-methyl-phenyl)-1-(3,4-dichloro-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester | HCID 68408658 | — |
Reaction Steps
The title compound was prepared from rac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester (Intermediate 9) and 5-bromo-2-iodotoluene in analogy to Example 1a): MS (ISP): 473.9 (M+H)+ and 373.9 ((M-Boc)+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367838B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-104d2032f4aa4238bc658a7bdd393eed |
| Source note | uspto-grants-2013_02 |