HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Methylsulfonyl)phenylboronic acid → Rac-[1-(3,4-dichloro-phenyl)-2-(3'-methanesulfonyl-biphenyl-3-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Methylsulfonyl)phenylboronic acid | HCID 2773542 | — |
| Reactant | Rac-[2-(3-bromo-phenyl)-1-(3,4-dichloro-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester | HCID 68408678 | — |
| Product | Rac-[1-(3,4-dichloro-phenyl)-2-(3'-methanesulfonyl-biphenyl-3-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester | HCID 68408642 | — |
Reaction Steps
The title compound was prepared from rac-[2-(3-Bromo-phenyl)-1-(3,4-dichloro-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester and 3-methylsulfonylphenylboronic acid in analogy to Example 1b): MS (ISP): 551.5 ((M+NH4)+, MS (ISN): 532.2 (M−H)−
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367838B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-16e0ee62cc3648d0bd1944ddac527ced |
| Source note | uspto-grants-2013_02 |