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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 384923Generated: October 31, 2026

3-Bromo-6-isopropoxy-2-methylpyridine → 1-(3,4-Dichloro-phenyl)-2-(6-isopropoxy-2-methyl-pyridin-3-yl)-2-oxo-ethyl-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/384923

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-6-isopropoxy-2-methylpyridineHCID 53217442—
ReactantRac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl esterHCID 87442373—
Product1-(3,4-Dichloro-phenyl)-2-(6-isopropoxy-2-methyl-pyridin-3-yl)-2-oxo-ethyl-carbamic acid tert-butyl esterHCID 68409964—

Reaction Steps

The title compound was prepared from rac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester (Intermediate 9) and 3-bromo-6-isopropoxy-2-methyl-pyridine (Intermediate 25) in analogy to Example 1a): MS (ISP): 453.2 and 455.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367838B2
Source datasetuspto-grants-2013_02
ORD IDord-17b8faac12ae4a3a9fe1e66e637a3072
Source noteuspto-grants-2013_02