HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-isopropoxy-4-methylpyridine → Rac-[1-(3,4-dichloro-phenyl)-2-(6-isopropoxy-4-methyl-pyridin-3-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-isopropoxy-4-methylpyridine | HCID 68410235 | — |
| Reactant | Rac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester | HCID 87442373 | — |
| Product | Rac-[1-(3,4-dichloro-phenyl)-2-(6-isopropoxy-4-methyl-pyridin-3-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester | HCID 68408270 | — |
Reaction Steps
The title compound was prepared from rac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester (Intermediate 9) and 5-bromo-2-isopropoxy-4-methyl-pyridine (Intermediate 28) in analogy to Example 1a): MS (ISP): 453.1 and 455.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367838B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-940f8561758a427a93a9f752b86fa2e8 |
| Source note | uspto-grants-2013_02 |