1-Iodo-4-(1,1,2,2-tetrafluoroethoxy)benzene → HCID 87443007, compound

HRID 384933Notes

Reaction equation

HRID 384933 reaction equation
[C:1]([O:5][C:6](=[O:23])[NH:7][CH:8]([C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[C:17]([Cl:22])[CH:16]=1)[C:9](=[O:14])N(OC)C)([CH3:4])([CH3:3])[CH3:2].I[C:25]1[CH:30]=[CH:29][C:28]([O:31][C:32]([F:37])([F:36])[CH:33]([F:35])[F:34])=[CH:27][CH:26]=1>>[C:1]([O:5][C:6](=[O:23])[NH:7][CH:8]([C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[C:17]([Cl:22])[CH:16]=1)[C:9](=[O:14])[C:25]1[CH:26]=[CH:27][C:28]([O:31][C:32]([F:36])([F:37])[CH:33]([F:35])[F:34])=[CH:29][CH:30]=1)([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 269853881-Iodo-4-(1,1,2,2-tetrafluoroethoxy)benzeneHCID 87442373Rac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester2×

Product 1

HCID 87443007HCID 87443007, compound

Procedure

The title compound was prepared from rac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester (Intermediate 9) and 1-iodo-4-(1,1,2,2-tetrafluoro-ethoxy)benzene in analogy to Example 1a): MS (ISN): 494.1 and 496.2 (M−H.

Sources & evidence

ORD record
ord-5f74d130b6d04f0b9bbda8438b7cdf90
Source dataset
uspto-grants-2013_02
Patent number
US08367838B2

Reaction notes

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