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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 384959Generated: October 27, 2026

p-Diiodobenzene → Rac-[1-(3-fluoro-4-methyl-phenyl)-2-(4-iodo-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/384959

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-DiiodobenzeneHCID 12208—
ReactantRac-[(3-fluoro-4-methyl-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl esterHCID 87443461—
ProductRac-[1-(3-fluoro-4-methyl-phenyl)-2-(4-iodo-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl esterHCID 68408268—

Reaction Steps

The title compound was prepared from rac-[(3-fluoro-4-methyl-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester (Intermediate 7) and 1,4-di-iodobenzene in analogy to Example 1a): MS (ISP): 470.0 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367838B2
Source datasetuspto-grants-2013_02
ORD IDord-142d8ed13ecd4d63882de797f3740484
Source noteuspto-grants-2013_02