Thionyl Chloride → HCID 49764772, compound

Participants

Reaction Conditions

Reaction Steps

After dissolving 2.0 g of 3,5-dimethyl-1-nitro-2-hexanol in 15 ml of toluene, 4.1 g of thionyl chloride and two drops of N,N-dimethylformamide were added thereto, and the solution was stirred for 2.5 hours at 80° C. The solution was cooled to room temperature and concentrated, and then purified by silica gel chromatography (hexane/ethyl acetate=8/1), thereby obtaining 1.5 g of 2-chloro-3,5-dimethyl-1-nitrohexane (yield: 72.4%).

Provenance & Evidence