Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 68108641 | HCID 68108641 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86668171 | HCID 86668171 | — |
Reaction Steps
To 3-t-butyl-4-methoxy-5-methylsulfonyl benzoic acid (200 mg), toluene (4 mL), N,N-dimethylformamide (1 droplet) and thionyl chloride (80 μL) were added to the solution, and then the mixture was stirred at 60° C. for 16 hours. The solvent was distilled off under reduced pressure and the obtained residue was azeotroped with toluene and used for the synthesis of (f).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08367843B2 |
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| Source dataset | uspto-grants-2013_02 |
|---|
| ORD ID | ord-fb017e0608244839961e397750ff4574 |
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| Source note | uspto-grants-2013_02 |
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