HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-2-Azido-1-[4-(benzyloxy)-3-[[(tert-butyldimethylsilyl)oxy]methyl]phenyl]ethanol → (R)-4-(2-Amino-1-hydroxyethyl)-2-[[(tert-butyldimethylsilyl)oxy]methyl]phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-2-Azido-1-[4-(benzyloxy)-3-[[(tert-butyldimethylsilyl)oxy]methyl]phenyl]ethanol | HCID 58505113 | — |
| Reactant | (R)-5-(2-Amino-1-((tert-butyldimethylsilyl)oxy)ethyl)-8-hydroxyquinolin-2(1H)-one | HCID 59023604 | — |
| Product | (R)-4-(2-Amino-1-hydroxyethyl)-2-[[(tert-butyldimethylsilyl)oxy]methyl]phenol | HCID 58505193 | — |
Reaction Steps
The title compound was synthesized in a manner analogous to that described in Intermediate 2, using Intermediate 7 as a substrate. ES/MS calcd. for C15H27NNaO3Si+ 320.2. found m/z=320.2 (M+Na)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367829B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-13c611b8132c4539a7e263009c90bcd6 |
| Source note | uspto-grants-2013_02 |