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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 385249Generated: October 26, 2026

(R)-N-[5-(2-Bromo-1-hydroxyethyl)-2-(phenylmethoxy)phenyl]formamide → (R)-N-[5-(2-Azido-1-hydroxyethyl)-2-(benzyloxy)phenyl]formamide

https://huagongshe.com/reaction/385249

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-N-[5-(2-Bromo-1-hydroxyethyl)-2-(phenylmethoxy)phenyl]formamideHCID 11142645—
Reactant(R)-5-(2-Azido-1-((tert-butyldimethylsilyl)oxy)ethyl)-8-(benzyloxy)quinolin-2(1H)-oneHCID 58505233—
Product(R)-N-[5-(2-Azido-1-hydroxyethyl)-2-(benzyloxy)phenyl]formamideHCID 58505134—

Reaction Steps

The title compound was synthesized in a manner analogous to that described for Intermediate 1, using Intermediate 9 as substrate. ES/MS calcd. C16H17N4O3+ 313.1. found m/z=313 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367829B2
Source datasetuspto-grants-2013_02
ORD IDord-d30cc0797b6b4d38bf30e127b110472d
Source noteuspto-grants-2013_02