反应详情

In analogy to Example 22A, the title compound was prepared from ethyl 4-chloro-5,7-dihydro-6H-pyrrolo[3′,4′:4,5]thieno[2,3-d]pyrimidine-6-carboxylate from Example 21A (250 mg, 0.88 mmol) and 3,4-dichloroaniline (150 mg, 0.93 mmol) to yield 324 mg (64% purity, 57% yield), which was used in the next step without purification.

1. customto yield 324 mg (64% purity, 57% yield), which
2. customwas used in the next step without purification