HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-5-(2-Amino-1-((tert-butyldimethylsilyl)oxy)ethyl)-8-hydroxyquinolin-2(1H)-one → (R)-N-[5-[2-Amino-1-[(tert-butyldimethylsilyl)oxy]ethyl]-2-hydroxyphenyl]methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-5-(2-Amino-1-((tert-butyldimethylsilyl)oxy)ethyl)-8-hydroxyquinolin-2(1H)-one | HCID 59023604 | — |
| Reactant | (R)-N-[5-[2-Azido-1-[(tert-butyldimethylsilyl)oxy]ethyl]-2-(benzyloxy)phenyl]methanesulfonamide | HCID 86659064 | — |
| Product | (R)-N-[5-[2-Amino-1-[(tert-butyldimethylsilyl)oxy]ethyl]-2-hydroxyphenyl]methanesulfonamide | HCID 66989965 | — |
Reaction Steps
The title compound was synthesized in a manner analogous to that described for Intermediate 2, using Intermediate 16 in place of Intermediate 1. The compound was used with no further purification. ES/MS calcd. for C15H29N2O4SSi+ 361.2. found m/z=361 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367829B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-8e9b7af6484a421e9ca727fa3d2ae02a |
| Source note | uspto-grants-2013_02 |