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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 385266Generated: October 30, 2026

8-Bromooctanoic acid → 8-Bromo-N-[[1,6-diethyl-4-[(tetrahydro-2H-pyran-4-yl)amino]-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl]octanamide

https://huagongshe.com/reaction/385266

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-Bromooctanoic acidHCID 548275—
ReactantN-[[1,6-Diethyl-4-[(tetrahydro-2H-pyran-4-yl)amino]-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl]-3-(2-oxopropyl)benzamideHCID 58505292—
Product8-Bromo-N-[[1,6-diethyl-4-[(tetrahydro-2H-pyran-4-yl)amino]-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl]octanamideHCID 58017300—

Reaction Steps

The title compound was synthesized in a manner analogous to that described for Intermediate 29, using 8-bromo-octanoic acid in place of 3-(2-oxopropyl)benzoic acid. ES/MS calcd. for C24H39BrN5O2+ 508.2. found m/z=508.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367829B2
Source datasetuspto-grants-2013_02
ORD IDord-99bec70ede26420181eec8ffd1bf45f7
Source noteuspto-grants-2013_02