HRID385281

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)Nc1ccc(C#CCCCBr)cc1

HCID58505295

未命名化合物

结构：CC(C)(C)OC(=O)Oc1ccc2c([C@H](CN(CCCCCCOCCCCc3ccc(N)cc3)C(=O)OC(C)(C)C)O[Si](C)(C)C(C)(C)C)ccc(OC(=O)OC(C)(C)C)c2n1

HCID66989909

未命名化合物

PRODUCTS

生成物

结构：CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)Nc1ccc(CCCCOCCCCCCN(C[C@H](O[Si](C)(C)C(C)(C)C)c2ccc(OC(=O)OC(C)(C)C)c3nc(OC(=O)OC(C)(C)C)ccc23)C(=O)OC(C)(C)C)cc1

HCID86659067

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in a manner analogous to that described for Intermediate 35, using Intermediate 42 in place of Intermediate 24. ES/MS calcd. for C65H99N8O12Si+ 1211.7. found m/z=1211.6 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-77de730316c143f7aa05722a8a22a8de
来源数据集: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08367829B2
来源说明: uspto-grants-2013_02

反应 SMILES

BrCCCC#CC1C=C[C:10]([NH:13][C:14]([NH:16][CH2:17][C:18]2[C:19]([NH:31][CH:32]3[CH2:37][CH2:36][O:35][CH2:34][CH2:33]3)=[C:20]3[CH:28]=[N:27][N:26]([CH2:29][CH3:30])[C:21]3=[N:22][C:23]=2[CH2:24][CH3:25])=[O:15])=[CH:9]C=1.NC1C=[CH:43][C:42]([CH2:45][CH2:46][CH2:47][CH2:48][O:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][N:56]([CH2:64][C@@H:65]([C:74]2[CH:83]=[CH:82][C:81]([O:84][C:85]([O:87][C:88]([CH3:91])([CH3:90])[CH3:89])=[O:86])=[C:80]3[C:75]=2[CH:76]=[CH:77][C:78]([O:92][C:93]([O:95][C:96]([CH3:99])([CH3:98])[CH3:97])=[O:94])=[N:79]3)[O:66][Si:67]([C:70]([CH3:73])([CH3:72])[CH3:71])([CH3:69])[CH3:68])[C:57](=[O:63])[O:58][C:59]([CH3:62])([CH3:61])[CH3:60])=[CH:41][CH:40]=1>>[C:96]([O:95][C:93]([O:92][C:78]1[CH:77]=[CH:76][C:75]2[C:80](=[C:81]([O:84][C:85]([O:87][C:88]([CH3:91])([CH3:90])[CH3:89])=[O:86])[CH:82]=[CH:83][C:74]=2[C@@H:65]([O:66][Si:67]([C:70]([CH3:73])([CH3:72])[CH3:71])([CH3:69])[CH3:68])[CH2:64][N:56]([CH2:55][CH2:54][CH2:53][CH2:52][CH2:51][CH2:50][O:49][CH2:48][CH2:47][CH2:46][CH2:45][C:42]2[CH:41]=[CH:40][C:10]([NH:13][C:14]([NH:16][CH2:17][C:18]3[C:19]([NH:31][CH:32]4[CH2:37][CH2:36][O:35][CH2:34][CH2:33]4)=[C:20]4[CH:28]=[N:27][N:26]([CH2:29][CH3:30])[C:21]4=[N:22][C:23]=3[CH2:24][CH3:25])=[O:15])=[CH:9][CH:43]=2)[C:57](=[O:63])[O:58][C:59]([CH3:62])([CH3:61])[CH3:60])[N:79]=1)=[O:94])([CH3:97])([CH3:98])[CH3:99]