HRID385282

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)[Si](C)(C)O[C@@H](CN)c1ccc(O)c2[nH]c(=O)ccc12

HCID59023604

未命名化合物

结构：CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(CC(C)(C)NC[C@H](O)c2ccc(OCc3ccccc3)c(CO)c2)c1

HCID66989983

未命名化合物

PRODUCTS

生成物

结构：CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(CC(C)(C)NC[C@H](O)c2ccc(O)c(CO)c2)c1

HCID66989422

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in a manner analogous to that described in Intermediate 2, using Intermediate 53 as substrate.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-801702d581d44b9fa8c6663719d26f9d
来源数据集: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08367829B2
来源说明: uspto-grants-2013_02

反应 SMILES

NC[C@@H](C1C=CC(O)=C2C=1C=CC(=O)N2)O[Si](C(C)(C)C)(C)C.C([O:31][C:32]1[CH:37]=[CH:36][C:35]([C@@H:38]([OH:75])[CH2:39][NH:40][C:41]([CH3:74])([CH3:73])[CH2:42][C:43]2[CH:44]=[C:45]([CH:70]=[CH:71][CH:72]=2)[C:46]([NH:48][CH2:49][C:50]2[C:51]([NH:63][CH:64]3[CH2:69][CH2:68][O:67][CH2:66][CH2:65]3)=[C:52]3[CH:60]=[N:59][N:58]([CH2:61][CH3:62])[C:53]3=[N:54][C:55]=2[CH2:56][CH3:57])=[O:47])=[CH:34][C:33]=1[CH2:76][OH:77])C1C=CC=CC=1>>[CH2:61]([N:58]1[C:53]2=[N:54][C:55]([CH2:56][CH3:57])=[C:50]([CH2:49][NH:48][C:46](=[O:47])[C:45]3[CH:70]=[CH:71][CH:72]=[C:43]([CH2:42][C:41]([NH:40][CH2:39][C@H:38]([OH:75])[C:35]4[CH:36]=[CH:37][C:32]([OH:31])=[C:33]([CH2:76][OH:77])[CH:34]=4)([CH3:74])[CH3:73])[CH:44]=3)[C:51]([NH:63][CH:64]3[CH2:65][CH2:66][O:67][CH2:68][CH2:69]3)=[C:52]2[CH:60]=[N:59]1)[CH3:62]