HRID385286

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：[N-]=[N+]=NC[C@H](O)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12

HCID58505170

未命名化合物

结构：CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(CNC[C@H](O)c2ccc(O)c(CO[Si](C)(C)C(C)(C)C)c2)c1

HCID58505276

未命名化合物

PRODUCTS

生成物

结构：CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(CNC[C@H](O)c2ccc(O)c(CO)c2)c1

HCID54588809

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

The title compound was synthesized in a manner analogous to that described for Intermediate 3, using HF pyridine in place of TBAF and Intermediate 45 as a substrate.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-5e09422cc6d44b44ad0e5dd8fd4a1ca3
来源数据集: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08367829B2
来源说明: uspto-grants-2013_02

反应 SMILES

N(C[C@@H](C1C=CC(OCC2C=CC=CC=2)=C2C=1C=CC(=O)N2)O)=[N+]=[N-].[Si]([O:33][CH2:34][C:35]1[CH:36]=[C:37]([C@@H:42]([OH:76])[CH2:43][NH:44][CH2:45][C:46]2[CH:47]=[C:48]([CH:73]=[CH:74][CH:75]=2)[C:49]([NH:51][CH2:52][C:53]2[C:54]([NH:66][CH:67]3[CH2:72][CH2:71][O:70][CH2:69][CH2:68]3)=[C:55]3[CH:63]=[N:62][N:61]([CH2:64][CH3:65])[C:56]3=[N:57][C:58]=2[CH2:59][CH3:60])=[O:50])[CH:38]=[CH:39][C:40]=1[OH:41])(C(C)(C)C)(C)C>N1C=CC=CC=1>[CH2:64]([N:61]1[C:56]2=[N:57][C:58]([CH2:59][CH3:60])=[C:53]([CH2:52][NH:51][C:49](=[O:50])[C:48]3[CH:73]=[CH:74][CH:75]=[C:46]([CH2:45][NH:44][CH2:43][C@H:42]([OH:76])[C:37]4[CH:38]=[CH:39][C:40]([OH:41])=[C:35]([CH2:34][OH:33])[CH:36]=4)[CH:47]=3)[C:54]([NH:66][CH:67]3[CH2:68][CH2:69][O:70][CH2:71][CH2:72]3)=[C:55]2[CH:63]=[N:62]1)[CH3:65]