HRID385287

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：[N-]=[N+]=NC[C@H](O)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12

HCID58505170

未命名化合物

结构：CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1ccc(CNC[C@H](O)c2ccc(O)c(CO[Si](C)(C)C(C)(C)C)c2)cc1

HCID66990074

未命名化合物

PRODUCTS

生成物

结构：CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1ccc(CNC[C@H](O)c2ccc(O)c(CO)c2)cc1

HCID54588810

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

The title compound was synthesized in a manner analogous to that described for Intermediate 3, using HF Pyridine in place of TBAF and Intermediate 46 as a substrate.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f602ccfa95df44ae99bbf6dd1ca5a0ed
来源数据集: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08367829B2
来源说明: uspto-grants-2013_02

反应 SMILES

N(C[C@@H](C1C=CC(OCC2C=CC=CC=2)=C2C=1C=CC(=O)N2)O)=[N+]=[N-].[Si]([O:33][CH2:34][C:35]1[CH:36]=[C:37]([C@@H:42]([OH:76])[CH2:43][NH:44][CH2:45][C:46]2[CH:75]=[CH:74][C:49]([C:50]([NH:52][CH2:53][C:54]3[C:55]([NH:67][CH:68]4[CH2:73][CH2:72][O:71][CH2:70][CH2:69]4)=[C:56]4[CH:64]=[N:63][N:62]([CH2:65][CH3:66])[C:57]4=[N:58][C:59]=3[CH2:60][CH3:61])=[O:51])=[CH:48][CH:47]=2)[CH:38]=[CH:39][C:40]=1[OH:41])(C(C)(C)C)(C)C>N1C=CC=CC=1>[CH2:65]([N:62]1[C:57]2=[N:58][C:59]([CH2:60][CH3:61])=[C:54]([CH2:53][NH:52][C:50](=[O:51])[C:49]3[CH:48]=[CH:47][C:46]([CH2:45][NH:44][CH2:43][C@H:42]([OH:76])[C:37]4[CH:38]=[CH:39][C:40]([OH:41])=[C:35]([CH2:34][OH:33])[CH:36]=4)=[CH:75][CH:74]=3)[C:55]([NH:67][CH:68]3[CH2:69][CH2:70][O:71][CH2:72][CH2:73]3)=[C:56]2[CH:64]=[N:63]1)[CH3:66]