反应详情

The title compound was synthesized in analogy to Example 12A from tert-butyl 4-chloro-5,6,7,9-tetrahydro-8H-pyrimido[5′,4′:4,5]thieno[2,3-c]azepine-8-carboxylate from Example 80A (1.74 g, 5.11 mmol) and 3,4-dichloroaniline (870 mg, 5.37 mmol) to yield 820 mg (44%).

1. customto yield 820 mg (44%)