反应详情

The title compound was prepared in analogy to Example 12A from tert-butyl 4-chloro-5,6,8,9-tetrahydro-7H-pyrimido[5′,4′:4,5]thieno[2,3-d]azepine-7-carboxylate from Example 84A (680 mg, 2.00 mmol) and 3-chloro-4-fluoroaniline (306 mg, 2.10 mmol) to yield 419 mg (60%).

1. customto yield 419 mg (60%)