HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-nitrothiophene-3-carboxamide → 5-[4-(3-Fluorooxetan-3-yl)phenyl]-2-nitrothiophene-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-nitrothiophene-3-carboxamide | HCID 53402948 | — |
| Reactant | 2-(4-(3-Fluorooxetan-3-yl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 59526072 | — |
| Product | 5-[4-(3-Fluorooxetan-3-yl)phenyl]-2-nitrothiophene-3-carboxamide | HCID 59526196 | — |
Reaction Steps
The title compound was prepared according to the general procedure in Intermediate 10 Step 5 using 5-bromo-2-nitrothiophene-3-carboxamide (Intermediate 10, Step 4) (0.31 g, 1.23 mmol) and 2-[4-(3-fluorooxetan-3-yl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (0.378 g, 1.36 mmol) as the starting materials.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367706B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-35293c296452406ba6724212a4d61b3a |
| Source note | uspto-grants-2013_02 |