4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl)morpholine → 5-(6-Morpholin-4-ylpyridin-3-yl)-2-nitrothiophene-3-carboxamide

Participants

Reaction Steps

The title compound was prepared from 5-bromo-2-nitrothiophene-3-carboxamide (Intermediate 10, Step 4) (2.50 g, 9.96 mmol) and 4-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-yl]morpholine (2.89 g, 9.96 mmol) according to the general procedure described in Intermediate 10, Step 5.

Provenance & Evidence