HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-nitrothiophene-3-carboxamide → 5-[4-(1,1-Dioxidothiomorpholin-4-yl)phenyl]-2-nitrothiophene-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-nitrothiophene-3-carboxamide | HCID 53402948 | — |
| Reactant | 4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)phenyl)thiomorpholine 1,1-dioxide | HCID 59525817 | — |
| Product | 5-[4-(1,1-Dioxidothiomorpholin-4-yl)phenyl]-2-nitrothiophene-3-carboxamide | HCID 59526272 | — |
Reaction Steps
The title compound was prepared from 5-bromo-2-nitrothiophene-3-carboxamide (Intermediate 10 Step 4) (300 mg, 1.20 mmol) and 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]thiomorpholine 1,1-dioxide (403 mg, 1.20 mmol) according to the general procedure described in Intermediate 10 Step 5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367706B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-87658383e03f4d0bacbb355eb7b07bdb |
| Source note | uspto-grants-2013_02 |