HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-nitrothiophene-3-carboxamide → 2-Amino-5-[4-(1,1-dioxidothiomorpholin-4-yl)phenyl]thiophene-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-nitrothiophene-3-carboxamide | HCID 53402948 | — |
| Reactant | 5-[4-(1,1-Dioxidothiomorpholin-4-yl)phenyl]-2-nitrothiophene-3-carboxamide | HCID 59526272 | — |
| Product | 2-Amino-5-[4-(1,1-dioxidothiomorpholin-4-yl)phenyl]thiophene-3-carboxamide | HCID 59525597 | — |
Reaction Steps
The title compound was prepared from 5-[4-(1,1-dioxidothiomorpholin-4-yl)phenyl]-2-nitrothiophene-3-carboxamide (366 mg, 0.96 mmol) according to the general procedure described in Intermediate 10 Step 6 (nitro reduction method A).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367706B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-f1c04a1cf5e04d23b48399107da6d740 |
| Source note | uspto-grants-2013_02 |