3-amino-2-methylbutan-2-ol → HCID 59525576, compound
Reaction equation
[Br:1][C:2]1[N:7]=[C:6]([CH:8]=O)[CH:5]=[CH:4][CH:3]=1.[NH2:10][CH:11]([CH3:16])[C:12]([CH3:15])([OH:14])[CH3:13]>>[Br:1][C:2]1[N:7]=[C:6]([CH2:8][NH:10][CH:11]([CH3:16])[C:12]([CH3:15])([OH:14])[CH3:13])[CH:5]=[CH:4][CH:3]=1Participants
3
Procedure
The title compound was prepared according to the procedure in Example 45, Step 1 using 6-bromopyridine-2-carbaldehyde (0.20 g, 1.08 mmol) and 3-amino-2-methylbutan-2-ol (0.11 g, 1.08 mmol) as the starting materials.
Sources & evidence
- ORD record
- ord-312b51868311464fa841d167ba273cc7
- Source dataset
- uspto-grants-2013_02
- Patent number
- US08367706B2
Reaction notes
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