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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 385769Generated: October 30, 2026

2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → HCID 25123815, compound

https://huagongshe.com/reaction/385769

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
Reactant(3S)-4-[(6-bromopyridin-2-yl)methyl]-3-methylmorpholineHCID 59526294—
ProductHCID 25123815HCID 25123815—

Reaction Steps

The title compound was prepared as described in Example 1 using 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (150 mg, 0.48 mmol) and (3S)-4-[(6-bromopyridin-2-yl)methyl]-3-methylmorpholine (133 mg, 0.49 mmol) as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367706B2
Source datasetuspto-grants-2013_02
ORD IDord-b47625fa16e54a9ab453091b2ac00fdb
Source noteuspto-grants-2013_02