Azetidine → 2-(1-Azetidin-1-ylethyl)-6-bromopyridine

HRID 385788Notes

Reaction equation

HRID 385788 reaction equation
[NH:1]1[CH2:4][CH2:3][CH2:2]1.[Br:5][C:6]1[N:11]=[C:10]([CH:12](O)[CH3:13])[CH:9]=[CH:8][CH:7]=1>>[N:1]1([CH:12]([C:10]2[CH:9]=[CH:8][CH:7]=[C:6]([Br:5])[N:11]=2)[CH3:13])[CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 10422AzetidineHCID 110634791-(6-Bromo-2-pyridinyl)ethanol

Product 1

HCID 595255652-(1-Azetidin-1-ylethyl)-6-bromopyridine

Procedure

The title compound was prepared according to the procedure in Example 139 Step 1 using azetidine (0.141 g, 2.48 mmol) and 1-(6-bromopyridin-2-yl)ethanol (0.500 g, 2.48 mmol) as the starting materials.

Sources & evidence

ORD record
ord-e0a417d8439d47fcbe34eceb59d05b73
Source dataset
uspto-grants-2013_02
Patent number
US08367706B2

Reaction notes

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