Potassium Hydroxide → 8-(2-Methoxy-5-methylmercapto-phenyl)-purin-6-one

HRID 3858Notes

Reaction equation

HRID 3858 reaction equation
Cl[C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[NH:4][C:5]([C:11]1[CH:16]=[C:15]([S:17][CH3:18])[CH:14]=[CH:13][C:12]=1[O:19][CH3:20])=[N:6]2.[OH-:21].[K+]>>[CH3:20][O:19][C:12]1[CH:13]=[CH:14][C:15]([S:17][CH3:18])=[CH:16][C:11]=1[C:5]1[N:4]=[C:3]2[C:7](=[N:8][CH:9]=[N:10][C:2]2=[O:21])[N:6]=1

Participants

3

Reactant 2

HCID 14797Potassium HydroxideHCID 540685716-Chloro-8-(2-methoxy-5-methylmercapto-phenyl)-purine

Product 1

HCID 543632758-(2-Methoxy-5-methylmercapto-phenyl)-purin-6-one

Procedure

Prepared analogously to Example 16 from 6-chloro-8-(2-methoxy-5-methylmercapto-phenyl)-purine by reaction with 20% potassium hydroxide solution.

Sources & evidence

ORD record
ord-1710e5d8571f49e99991ce847c7586f7
Source dataset
uspto-grants-1988_02
Patent number
US04722929

Reaction notes

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