Hydrochloric Acid → HCID 59526017, compound

Participants

Reaction Conditions

Reaction Steps

Ethyl N-[(benzyloxy)carbonyl]-N-[(6-bromopyridin-2-yl)methyl]glycinate (0.21 g, 0.52 mmol) was dissolved in methanol (5.1 mL) and tert-butanol (5.1 mL). Potassium hydroxide (2.6 mL, 2.60 mmol) was added and the reaction was heated at 60° C. for two hours. The reaction was made acidic with 1M hydrochloric acid and the product extracted with ethyl acetate. The organic layer was then dried over magnesium sulfate, filtered and concentrated. The product was used without further purification to yield the title compound.

Provenance & Evidence