6-Bromopyridine-2-carbaldehyde → HCID 59526375, compound

HRID 385829Notes

Reaction equation

HRID 385829 reaction equation
[Br:1][C:2]1[N:7]=[C:6]([CH:8]=O)[CH:5]=[CH:4][CH:3]=1.Cl.[CH:11]1([NH:16][C:17](=[O:20])[CH2:18][NH2:19])[CH2:15][CH2:14][CH2:13][CH2:12]1>>[Br:1][C:2]1[N:7]=[C:6]([CH2:8][NH:19][CH2:18][C:17]([NH:16][CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[O:20])[CH:5]=[CH:4][CH:3]=1

Participants

3

Procedure

The title compound was prepared by using the procedure listed in Example 47, Step 7 with 6-bromopyridine-2-carbaldehyde (1.0 g, 5.38 mmol) and N-cyclopentylglycinamide hydrochloride (0.96 g, 5.38 mmol) as the starting materials.

Sources & evidence

ORD record
ord-a94ef13c6395440299ea8db6cec239ff
Source dataset
uspto-grants-2013_02
Patent number
US08367706B2

Reaction notes

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