反应详情

In analogy to Example 89, the title compound was prepared from N-(3-ethynylphenyl)-6,7-dihydro-5H-pyrrolo[3′,4′:4,5]thieno[2,3-d]pyrimidin-4-amine from Example 27A (40 mg, 0.12 mmol) and (2E)-4-(dimethylamino)but-2-enoic acid hydrochloride from Example 1A (27 mg, 0.17 mmol) to yield 11 mg (22%).

1. customto yield 11 mg (22%)