HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2E)-4-(Dimethylamino)-2-butenoic acid hydrochloride → HCID 58116956, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2E)-4-(Dimethylamino)-2-butenoic acid hydrochloride | HCID 45358758 | — |
| Reactant | N-(3,4-Dichlorophenyl)-5,6,7,8-tetrahydropyrido[4',3':4,5]furo[2,3-d]pyrimidin-4-amine | HCID 58116965 | — |
| Product | HCID 58116956 | HCID 58116956 | — |
Reaction Steps
In analogy to Example 89, the title compound was prepared from N-(3,4-dichlorophenyl)-5,6,7,8-tetrahydropyrido[4′,3′:4,5]furo[2,3-d]pyrimidin-4-amine from Example 41A (100 mg, 0.30 mmol) and (2E)-4-(dimethylamino)but-2-enoic acid hydrochloride from Example 1A (69 mg, 0.42 mmol) to yield 75 mg (56%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08524722B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-1f664c3939164f5cb0b90f35d5bd664b |
| Source note | uspto-grants-2013_09 |