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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 38591Generated: October 29, 2026

(2E)-4-(Dimethylamino)-2-butenoic acid hydrochloride → HCID 58116956, compound

https://huagongshe.com/reaction/38591

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2E)-4-(Dimethylamino)-2-butenoic acid hydrochlorideHCID 45358758—
ReactantN-(3,4-Dichlorophenyl)-5,6,7,8-tetrahydropyrido[4',3':4,5]furo[2,3-d]pyrimidin-4-amineHCID 58116965—
ProductHCID 58116956HCID 58116956—

Reaction Steps

In analogy to Example 89, the title compound was prepared from N-(3,4-dichlorophenyl)-5,6,7,8-tetrahydropyrido[4′,3′:4,5]furo[2,3-d]pyrimidin-4-amine from Example 41A (100 mg, 0.30 mmol) and (2E)-4-(dimethylamino)but-2-enoic acid hydrochloride from Example 1A (69 mg, 0.42 mmol) to yield 75 mg (56%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08524722B2
Source datasetuspto-grants-2013_09
ORD IDord-1f664c3939164f5cb0b90f35d5bd664b
Source noteuspto-grants-2013_09