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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 385920Generated: November 1, 2026

2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → HCID 59525747, compound

https://huagongshe.com/reaction/385920

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
ReactantPyridine, 2-bromo-6-[(methylsulfonyl)methyl]-HCID 59526086—
ProductHCID 59525747HCID 59525747—

Reaction Steps

The title compound was prepared using the procedure described in Example 1 with 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (0.075 g, 0.24 mmol) and 2-bromo-6-[(methylsulfonyl)methyl]pyridine (0.060 g, 0.24 mmol) as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367706B2
Source datasetuspto-grants-2013_02
ORD IDord-32ad0d04a2444dceae7a855d1d659358
Source noteuspto-grants-2013_02