1-(6-Bromopyridin-2-yl)pyrrolidin-3-ol → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[6-(3-hydroxypyrrolidin-1-yl)pyridin-2-yl]amino}thiophene-3-carboxamide

Beteiligte Stoffe

Reaktionsschritte

The title compound was prepared according to the procedure described in Example 1 using 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (200 mg, 0.64 mmol) and 1-(6-bromopyridin-2-yl)pyrrolidin-3-ol (132 mg, 0.54 mmol) as the starting materials.

Herkunft & Nachweise