Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl bromoacetate | HCID 60984 | — |
| Reactant | HCID 59526306 | HCID 59526306 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 59526011 | HCID 59526011 | — |
Reaction Steps
Potassium Carbonate (740 mg, 5.36 mmol), methyl bromoacetate (0.37 mL, 4.02 mmol) and 2-bromo-6-(1H-pyrazol-4-yl)pyridine (Example 398, Step 1) were taken up in acetonitrile. The mixture was heated at 70° C. for 72 hours. It was then poured into 300 mL diethyl ether and 50 mL water. The organic layer was separated, dried over magnesium sulfate, filtered, and concentrated to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08367706B2 |
|---|
| Source dataset | uspto-grants-2013_02 |
|---|
| ORD ID | ord-0efa27e1e20b4defaa721933fc6c5c7c |
|---|
| Source note | uspto-grants-2013_02 |
|---|
