反应详情

In analogy to Example 89, the title compound was prepared from N-(3-ethynylphenyl)-5,6,7,8-tetrahydropyrido[4′,3′:4,5]furo[2,3-d]pyrimidin-4-amine from Example 43A (100 mg, 0.344 mmol) and (2E)-4-(dimethylamino)but-2-enoic acid hydrochloride from Example 1A (80 mg, 0.48 mmol) to yield 66 mg (46%).

1. customto yield 66 mg (46%)