(2E)-4-(Dimethylamino)-2-butenoic acid hydrochloride → HCID 58116845, compound

Participants

Reaction Steps

In analogy to Example 89, the title compound was prepared from 4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-5,6,7,8-tetrahydrothieno[2,3-b:5,4-c′]dipyridine-3-carbonitrile from Example 57A (100 mg, 0.22 mmol) and (2E)-4-(dimethylamino)but-2-enoic acid hydrochloride from Example 1A (52 mg, 0.31 mmol) to yield 71 mg (53%).

Provenance & Evidence