2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-({5-[3-(2-hydroxyethyl)-1,2,4-oxadiazol-5-yl]-6-methylpyridin-2-yl}amino)thiophene-3-carboxamide

Participants

Reaction Steps

The title compound was prepared as described in Example 1 using 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (51 mg, 0.17 mmol) and 2-[5-(6-chloro-2-methylpyridin-3-yl)-1,2,4-oxadiazol-3-yl]ethanol (40 mg, 0.17 mmol) as starting materials.

Provenance & Evidence