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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 385976Generated: October 30, 2026

2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → HCID 178433134, compound

https://huagongshe.com/reaction/385976

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
Reactant6-Chloro-2-methyl-3-(1H-1,2,3-triazol-4-yl)pyridineHCID 178432861—
ProductHCID 178433134HCID 178433134—

Reaction Steps

The title compound was prepared as described in Example 1 using 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (60 mg, 0.19 mmol) and 6-chloro-2-methyl-3-(1H-1,2,3-triazol-4-yl)pyridine (Example 433, Step 3) (59 mg, 0.19 mmol) as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367706B2
Source datasetuspto-grants-2013_02
ORD IDord-31fa9f311d254f16a49aa832d558637b
Source noteuspto-grants-2013_02