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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 385978Generated: November 1, 2026

2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → HCID 59525567, compound

https://huagongshe.com/reaction/385978

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
ReactantHCID 59526305HCID 59526305—
ProductHCID 59525567HCID 59525567—

Reaction Steps

The title compound was prepared as described in Example 1 using 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (150 mg, 0.48 mmol) and 1-[(6-chloro-2-methylpyridin-3-yl)methoxy]-2-methylpropan-2-ol (110 mg, 0.48 mmol) as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367706B2
Source datasetuspto-grants-2013_02
ORD IDord-9dda81df1b774eefb115e5391b1c34e5
Source noteuspto-grants-2013_02