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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 386012Generated: October 30, 2026

2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → HCID 59526073, compound

https://huagongshe.com/reaction/386012

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
Reactant2-(6-Chloro-2-fluoropyridin-3-yl)propan-2-olHCID 59525941—
ProductHCID 59526073HCID 59526073—

Reaction Steps

The title compound was prepared as described in Example 1 using, 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (52 mg, 0.17 mmol) and 2-(6-chloro-2-fluoropyridin-3-yl)propan-2-ol (32 mg, 0.17 mmol) as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367706B2
Source datasetuspto-grants-2013_02
ORD IDord-f9ecbaf070814eb28ab457024e8cb644
Source noteuspto-grants-2013_02