HCID 131730200, compound → HCID 59526378, compound

Participants

Reaction Steps

tert-Butyl methyl[(6-chloro-2-methylpyridin-3-yl)methyl]imidodicarbonate (830 mg, 2.64 mmol) was taken up in a mixture of CH2Cl2 (8.0 ml) and TFA (2.0 ml) and stirred at room temperature for 1 h. The solution was concentrated, diluted with EtOAc, and washed with saturated NaHCO3. The organic layer was washed with brine, dried (MgSO4), filtered, and evaporated. Flash chromatography (25-100% EtOAc/hexanes) afforded the title compound as a colorless solid.

Provenance & Evidence