2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 5-[2-Fluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-({6-[2-hydroxy-1-(1H-1,2,3-triazol-1-yl)ethyl]pyridin-2-yl}amino)thiophene-3-carboxamide

Participants

Reaction Steps

The title compound was synthesized from 2-(6-bromopyridin-2-yl)-2-(1H-1,2,3-triazol-1-yl)ethanol (110 mg, 0.41 mmol) and 2-amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (120 mg, 0.41 mmol) according to the general procedure in Example 1.

Provenance & Evidence