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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 386058Generated: November 3, 2026

2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → HCID 59525600, compound

https://huagongshe.com/reaction/386058

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
ReactantHCID 59526244HCID 59526244—
ProductHCID 59525600HCID 59525600—

Reaction Steps

The title compound was synthesized from 2-[1-(6-chloropyridin-2-yl)-1H-1,2,3-triazol-4-yl]ethanol (90 mg, 0.40 mmol) and 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (125 mg, 0.40 mmol) according to the general procedure in Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367706B2
Source datasetuspto-grants-2013_02
ORD IDord-9ed2357d10f9456bbfcb2add418c9dcd
Source noteuspto-grants-2013_02