HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxypyrrolidine → 1-(4-Ethoxypyrimidin-2-yl)pyrrolidin-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxypyrrolidine | HCID 98210 | — |
| Reactant | 2-Chloro-4-ethoxypyrimidine | HCID 4737280 | — |
| Product | 1-(4-Ethoxypyrimidin-2-yl)pyrrolidin-3-ol | HCID 59526242 | — |
Reaction Steps
The title compound was prepared as described in Example 555, Step 2 using 2-chloro-4-ethoxypyrimidine (2.4 g, 15 mol) and pyrrolidin-3-ol (1.6 g, 18 mmol) as the starting materials.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367706B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-22a0f1e4b62d4514b25f48f32606bca5 |
| Source note | uspto-grants-2013_02 |