2-(Morpholin-2-yl)ethan-1-ol → HCID 59526309, compound

HRID 386114Notes

Reaction equation

HRID 386114 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([CH:8]=O)[N:3]=1.[NH:10]1[CH2:15][CH2:14][O:13][CH:12]([CH2:16][CH2:17][OH:18])[CH2:11]1>>[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([CH2:8][N:10]2[CH2:15][CH2:14][O:13][CH:12]([CH2:16][CH2:17][OH:18])[CH2:11]2)[N:3]=1

Participants

3

Reactant 2

HCID 159361322-(Morpholin-2-yl)ethan-1-olHCID 513419564-Chloropyrimidine-2-carbaldehyde

Product 1

HCID 59526309HCID 59526309, compound

Procedure

The title compound was prepared as described in Example 106, Step 1 with 4-chloropyrimidine-2-carbaldehyde (110 mg, 0.84 mmol) and 2-morpholin-2-ylethanol (100 mg, 0.70 mmol) as starting materials.

Sources & evidence

ORD record
ord-b0540f05804f4f03a151eff490afc582
Source dataset
uspto-grants-2013_02
Patent number
US08367706B2

Reaction notes

Loading…